Abstract
The earliest descriptions of essential tremor (ET) in the 19th century reported isolated tremor as a benign “constitutional property” of sufferers that was absolutely heritable. Contemporary experts debate most of these issues. ET is arguably the most prevalent movement disorder in the community, affecting up to 14% of people over 65 years of age. It is most often benign and to a large extent hereditary, but despite this no monogenetic causes of ET have been identified. A proportion of patients with ET have cognitive slowing, cerebellar signs or parkinsonism, suggesting an association with broader neurological dysfunction than isolated tremor.
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