Abstract

Atopic dermatitis (AD) is a chronic, inflammatory skin disease characterized by significant barrier damage. Since the regulation and maintenance of the antimicrobial and permeability skin barriers are closely connected, and the literature data regarding the expression of AMPs in AD are controversial (mainly suggesting their decreased level), we aimed to comprehensively investigate the expression of different AMPs in lesional (AD L) and non-lesional (AD NL) skin samples both at the mRNA (qRT-PCR) and the protein levels (immunohistochemistry).

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