Abstract

Introduction and aims of the study: Recurrent pregnancy loss (RPL) affects 2-5% of couples with unexplained etiology. Interleukins are important mediators in the implantation. IL1B is crucial for the regulation of immune responsiveness which is necessary for a successful pregnancy. IL6 is involved in the mechanism of embryonic implantation and placental development. Interleukin gene polymorphisms have been previously associated with risk of pregnancy loss in various populations affecting the maintenance of pregnancy.

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