Abstract
Background: Chronic kidney disease (CKD) is a pathological process hallmarked by progressive decline of kidney function and most likely end up in kidney failure state. Hemodialysis (HD) is one of the main therapy for CKD, where the goal is to replace renal function in maintaining fluid and acid-base-electrolyte balance, excreting metabolism waste and controlling blood pressure. Intradialytic hypertension (IDH) is a possible complication during HD. Interdialytic Weight Gain (IDWG) is a risk factor of IDH. Objective: To acknowledge relation between IDWG and IDH incidence in CKD patients. Method: This is analytic observational cross sectional study that was carried out from November–December 2020. Patients with CKD aged ≥18 years old and had routine HD twice a week for at least 3 months. IDWG = [(current pre dialysis weight – previous post dialysis weight)/dry weight × 100%]. Dry weight was defined by body weight without clinical sign of fluid retention. IDWG were categorized into 3 groups: <3% (group I); 3.1–3.9% (group II); >3.9% (group III). IDH was defined by increasing in systolic blood pressure >10 mmHg after at least 4 of 6 consecutive HD sessions. Blood pressure was measured 30 minutes before and after HD. Patients who did not finish at least 4 HD sessions, refused informed consent, and whose body weight unobtainable were excluded. Data was analyzed using chi square with significance level of p < 0.05 and confidence interval (CI) 95%. Result: 140 patients were included in this study (70 male, 70 female). IDH were found in all 3 IDWG groups: group I 37%, group II 80%, and group III 93.1%. Data analysis showed a significant relation between IDWG and IDH (p = 0.0001). Conclusion: There is a significant relation between IDWG and incidence of IDH.
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