Abstract
Introduction Pregnancy is hypercoagulable state. The tendency to thrombosis, has been developed rapidly and has been linked to many aspects of pregnancy. It is recently that severe pregnancy complications such as severe preeclampsia, intrauterine growth retardation, abruptio placentae and stillbirth has been shown to be associated with thrombophilia. The obstetrics service of the Federal University of Juiz de Fora has an Ambulatory for the attendance of pregnant women with poor obstetric result and this study was taken. Methods Study was performed when 79 a coort study with poor obstetric results (hypertensive syndromes, intrauterine fetal death, abortium, intrauterina growth retardation, abruption placentae) were evaluated. All those patients were submitted to trombophiilia research (V Leiden factor, mutation of prothrombin, SAAF, MTHFR, protein S, protein C, antithrombin III and PAI 4G/5G mutation). Results The mutation PAI 4G/5G was associated to abortium (p Conclusions The authors conclude that this mutation should be searched in the effective effects of the fetal result.
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