Abstract
Porosity is a key parameter in the design of tissue engineering scaffolds, as bioactivity can be controlled and tailored to the synthesis of the target tissue by finely tuning the porous structure of the scaffolding biomaterial. This chapter discusses the effect of structural parameters, such as pore volume fraction, pore size and distribution, pore shape, pore interconnectivity and pore orientation, on the performance of sponge-like scaffolds, with a special focus on those directed to nerve regeneration.
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