4-Methylpyridinium chloride ionic liquid grafted on Mn@zeolite-Y: Design, fabrication and performance as a novel multi-functional nanocatalyst in the four-component synthesis of pyrazolophthalazine-diones

Abstract

In this work, 4-methylpyridinium chloride (4-MePy-Cl) ionic liquid grafted on nanoporous Mn/zeolite-Y was synthesized in several steps. First, Mn@zeolite-Y nanostructure was prepared by the metal exchange reaction of manganese (II) chloride with zeolite-NaY. This nanomaterial was then reacted consecutively with trimethoxysilylpropyl chloride and 4-methylpyridine to obtain multi-functional 4-MePy-Cl ionic liquid manganese nanocomposite (Mn/4-MePy-IL@ZY) for the first time. The structure of this nanoporous compound was confirmed using different characterization techniques such as FT-IR, FE-SEM, EDX, XRD, N 2 adsorption-desorption (BET), and TGA analyses. To evaluate the catalytic performance, the catalyst obtained was successfully employed as a multi-functional and efficient nanocatalyst in the facile synthesis of 3-amino-1-aryl-5,10-dioxo-pyrazolo [(Jagadeesan, 2016; Srilakshmi and Saraf, 2018) 1,21,2-b]phthalazine-2-carbonitriles through the four-component reaction of phthalic anhydride, hydrazine hydrate, malononitrile and arylaldehydes under mild reaction conditions with excellent yields. One of the obvious advantages of this nanocatalyst is the presence of Lewis acid (Mn 2+ ) and basic ionic liquid (4-MePy-Cl) sites on a nanoporous solid surface (multi-functional), which can be very useful and important in multi-component syntheses. • Designing new multi-functional nano-system of zeolitic micro-mesoporous is noteworthy advantage. • The Mn/4-MePy-IL@zeolite-Y acts as catalyst in the four-component synthesis of pyrazolophthalazines under green conditions. • Multi-functional nanocatalysts can be very useful and important in multi-component syntheses. • This procedure is eco-friendly, economically viable and versatile.