Abstract
RECENT investigations1 of the behaviour of the Dische reagent2 towards various deoxysugars and their glycosides have revealed that a coloration is obtained with a number of such compounds, and that the reagent cannot be regarded as specific for 2-deoxy-ribose. Colorimetric evidence based on the Disehe test thus does not preclude the occurrence of deoxysugars other than 2-deoxy ribose3 in the deoxy-pentose nucleic acid structure. As an extension to the investigations on the known 2-deoxyribose4 and 3-deoxyribose5 (otherwise known as 3-deoxyxylose), we have synthesized 4-deoxy-L-ribose, with a view to its characterization and the study of its behaviour towards colorimetric reagents.
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