4-Alkoxy- and 4-Amino-2,2‘-bipyrrole Synthesis

Abstract

[Structure: see text] 4-alkoxy-2,2'-bipyrroles and the first examples of 4-amino-2,2'-bipyrroles have been synthesized by a diversity-oriented strategy from 4-hydroxyproline. The bipyrrole products offer interesting potential as building blocks for making pyrrole products, as demonstrated by the first synthesis of an amino prodigiosin analogue.