Abstract
AbstractIn a search for small organic molecules as catalysts for the direct asymmetric Michael addition reaction of aldehydes to nitrostyrenes, 4,4′‐di(naphthalene‐1‐ylmethyl)‐L‐proline 1c and a catalytic amount of 4‐dimethylaminopyridine (DMAP) were found to be an efficient system for the Michael addition of aldehydes to nitrostyrenes with high diastereo‐ and enantioselectivity and broad substrate range.
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