(4+2) Dimerization of imides of arylmaleic acids in the presence of the 3,5-dimethyl-1 H-pyrazole and 2,6-lutidine

Abstract

Imides of arylmaleic acids in the presence of 3,5-dimethyl-1 H-pyrazole underwent (4+2) dimerization under heating in chlorobenzene within 24 h to afford 1,2,3,3a,3b,4,5,6,6a,10b-decahydrobenzo[ e]pyrrolo[3,4- g]isoindole-1,3,4,6-tetraones in good yields. It was established that during the heating of imides of arylmaleic acid in 2,6-lutidine at 100 °C the (4+2) dimerization products containing a lutidine fragment are obtained.