Abstract

HYPR TRICKS is an acquisition method that combines radial k-space trajectories, sampling k-space at different rates (TRICKS), and a new strategy for image reconstruction that uses highly constrained backprojection reconstruction (HYPR). This approach provides 3D time-resolved contrast-enhanced MR angiograms of the cerebral vessels with subsecond frame update times and submillimeter in-plane spatial resolution. Artifacts are suppressed, and signal-to-noise ratio is well maintained, by using HYPR reconstruction.

Highlights

  • For several decades, time-resolved serial imaging using x-ray digital subtraction angiography has played a major role in the diagnosis of vascular disease.[1]

  • Time-resolved contrast-enhanced MR angiography is essential for the characterization of high-flow lesions[9,10] such as arteriovenous malformations (AVMs) and dural fistulas.[11,12]

  • For this study, the highly constrained backprojection reconstruction (HYPR) TRICKS method was used to acquire 3D time-resolved contrast-enhanced MR angiograms of the cerebral vessels in 14 healthy subjects and 2 patients with AVMs, by using a protocol that was approved by the institutional review board

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Summary

Methods and Subjects

The HYPR TRICKS method was used to acquire 3D time-resolved contrast-enhanced MR angiograms of the cerebral vessels in 14 healthy subjects and 2 patients with AVMs, by using a protocol that was approved by the institutional review board. Angular undersampling was applied to the radial trajectories that formed each timeframe such that the number of radial lines per frame, Nr, was much smaller than that which is traditionally understood to be the minimum necessary to accurately reconstruct the object being imaged (the Nyquist sampling criterion). These Nr radial lines were evenly distributed over a full circle in the kx–ky plane for each frame. On 4 healthy subjects and 2 patients with AVMs, 2 acquisition methods, HYPR TRICKS and Cartesian TRICKS, were performed on the 3T scanner during a 1-hour scanning session with approximately a 20-minute interval between the 2 injections. Administration of the contrast material was followed immediately by a 25-mL saline flush injected at the same rate as that of the contrast material

Results
Discussion
Conclusions
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