3D real-time micromechanical compressive behaviour of bone–cement interface: Experimental and finite element studies

Abstract

The integrity of bone–cement interface is essential for the long-term stability of cemented total joint arthroplasty. Although several studies have been carried out on bone–cement interface at continuum level, micromechanics of the interface has been studied only recently for tensile and shear loading cases. Fundamental studies of bone–cement interface at microstructural level are critical to the understanding of the failure processes of the interface, where multiple factors may contribute to failure. Here we present a micromechanical study of bone–cement interface under compression, which utilised in situ mechanical testing, time-lapsed microcomputed tomography (CT) and finite element (FE) modelling. Bovine trabecular bone was used to interdigitate with bone cement to obtain bone–cement interface samples, which were tested in step-wise compression using a custom-made loading stage within the μCT chamber. A finite element model was built from the CT images of one of the tested samples and loaded similarly as in the experiment. The simulated stress-displacement response fell within the range of the experimental responses, and the predicted local strain distribution correlated well with the failure pattern in the subject-specific experimental model. Damage evolution with load in the samples was monitored both experimentally and numerically. The results from the FE simulations further revealed the development of damage in the regions of interest during compression, which may be useful towards a micromechanics understanding of the failure processes at bone–cement interface.