Abstract
Quantitative photoacoustic tomography involves the construction of a photoacoustic image from surface measurements of photoacoustic wave pulses and the recovery of the optical properties of the imaged region. This is a nonlinear, ill-posed inverse problem, for which model-based inversion techniques have been proposed. Here, the radiative transfer equation is used to model the light propagation, and the acoustic propagation and image reconstruction are included. In other words, the full quantitative inversion is tackled. Since Newton-based minimisations are impractical when dealing with three-dimensional images, an adjoint-assisted gradient-based inversion was used as a practical alternative to determining the optical coefficients.
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