Abstract
Background 3D dark-blood MRI techniques have shown great potential in coronary plaque burden assessment [1]. However, a substantial variability in quantification could result from superficial calcification that often mimics part of lumen because of low signal. Recent work showed that gray-blood contrast can help to separate superficial calcification from lumen [2]. Thus, the purpose of this study was to develop a 3D coronary dark-blood interleaved with gray-blood (cDIG) MRI technique that potentially improve the visualization and quantification of coronary plaque.
Highlights
3D dark-blood MRI techniques have shown great potential in coronary plaque burden assessment [1]
Methods sequence design The coronary dark-blood interleaved with gray-blood (cDIG) method is developed based on a balanced SSFP sequence combined with a local reinversion (LocReInv) preparation as proposed by Botnar et al [3]
As with the LocReInv protocol, double inversion pulses are applied every two heartbeats and dark-blood images are collected in the first heartbeat
Summary
3D dark-blood MRI techniques have shown great potential in coronary plaque burden assessment [1]. A substantial variability in quantification could result from superficial calcification that often mimics part of lumen because of low signal. Recent work showed that gray-blood contrast can help to separate superficial calcification from lumen [2]. The purpose of this study was to develop a 3D coronary dark-blood interleaved with gray-blood (cDIG) MRI technique that potentially improve the visualization and quantification of coronary plaque
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