Abstract
Fourier ptychography tomography (FPT) is a novel computational technique for coherent imaging in which the sample is numerically reconstructed from images acquired under various illumination directions. FPT is able to provide three-dimensional (3D) reconstructions of the complex sample permittivity with an increased resolution compared to standard microscopy. In this work, FPT is applied to coherent anti-Stokes Raman scattering (CARS) imaging. We show on synthetic data that complex third-order susceptibilities can be reconstructed in 3D from a limited number of widefield CARS images. In addition, we observe that the non-linear interaction increases significantly the potential of CARS-FPT compared to linear FPT in terms of resolution. In particular, with a careful choice of the pump and Stokes beam directions, CARS-FPT is able to provide optical sectioning even in transmission configuration.
Highlights
Fourier ptychography (FP) is a versatile technique with great potential for research and industrial applications [1]
It is worth noting that this issue is not encountered in classical linear Fourier ptychography tomography (FPT) where the recorded intensity can be modeled as the interference pattern between the specular transmitted field and the field diffracted by the sample
In this work we presented a numerical study of the performances of 3D coherent anti-Stokes Raman scattering Fourier ptychography tomography (CARS-FPT)
Summary
Fourier ptychography (FP) is a versatile technique with great potential for research and industrial applications [1]. It consists in reconstructing numerically the sample from multiple images recorded under different orientations of a collimated beam [2]. Relevant for all coherent imaging techniques, FP was first developed in the domain of optical microscopy but soon extended to X-ray [3] and near infra-red [4] imaging It appeared as a simple approach for improving the lateral resolution [2, 5], or more precisely the space-bandwidth product (SBP) of the imager and, most importantly could image both phase and absorptive objects [6]. It can be used to estimate the aberrations of imaging systems [7]
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