Abstract
In this contribution we will discuss the experimental application of 3D chiral metamaterials as high sensitivity biosensors, exploiting circular dichroism in transmission. 3D metamaterials with chiral features can be realized by highly accurate and highly localized bottom-up nanofabrication approach. Large chiroptical effects can be engineered, originating from the single element optical resonances, but collective interactions in arrayed configurations can play a significant role, further enhancing these effects. Capability of biomarker detection in the femtomolar range is demonstrated even in complex biofluid matrix.
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