Year-end Sale % OFF 
Abstract
Background 13C Dynamic Nuclear Polarization (DNP) with rapid dissolution together with Magnetic Resonance Chemical Shift Imaging (CSI) have been used for non-invasive real-time metabolic assessment in cardiac experimental models on a clinical 3T scanner. Here, we report an in vivo comparison of hyperpolarized [1-13C] pyruvate and [1-13C] acetate perfusion and metabolism: a method based on a 3D Spiral CSI sequence is presented for obtaining spatially and spectrally-resolved information on whole heart cardiac metabolism.
Highlights
13C Dynamic Nuclear Polarization (DNP) with rapid dissolution together with Magnetic Resonance Chemical Shift Imaging (CSI) have been used for non-invasive real-time metabolic assessment in cardiac experimental models on a clinical 3T scanner
We report an in vivo comparison of hyperpolarized [1-13C] pyruvate and [1-13C] acetate perfusion and metabolism: a method based on a 3D Spiral CSI sequence is presented for obtaining spatially and spectrally-resolved information on whole heart cardiac metabolism
A graph of the g-variate and mono-exponential fitting of hyperpolarized [1-13C] acetate myocardial spectroscopic signals is reported in Figure 1 while a representative map in short axis (SA) orientation through the heart is shown in Figure 2: [1-13C] acetate is extracted inside the heart and clearly detected in the heart-chambers and myocardial wall
Summary
13C Dynamic Nuclear Polarization (DNP) with rapid dissolution together with Magnetic Resonance Chemical Shift Imaging (CSI) have been used for non-invasive real-time metabolic assessment in cardiac experimental models on a clinical 3T scanner. We report an in vivo comparison of hyperpolarized [1-13C] pyruvate and [1-13C] acetate perfusion and metabolism: a method based on a 3D Spiral CSI sequence is presented for obtaining spatially and spectrally-resolved information on whole heart cardiac metabolism
Sign-in/Register to view highlights & summary Talk to us
Join us for a 30 min session where you can share your feedback and ask us any queries you have
Schedule a callDisclaimer: All third-party content on this website/platform is and will remain the property of their respective owners and is provided on "as is" basis without any warranties, express or implied. Use of third-party content does not indicate any affiliation, sponsorship with or endorsement by them. Any references to third-party content is to identify the corresponding services and shall be considered fair use under The CopyrightLaw.
