Abstract
A novel 3D bioprinting of porous scaffold was developed by using highly concentrated alginate/polyvinyl alcohol (PVA) as building block for tissue engineering. PVA sols were partly diffused from the printed scaffolds during incubation in CaCl2 solution, creating plenty of micropores in scaffolds. The properties of the as-prepared scaffolds such as porosity, water adsorption and mechanical properties, can be tailored by adjusting the mass ratio of alginate/PVA. Meanwhile, bovine serum albumin and bone morphogenetic protein 2 were successfully co-printed into scaffolds, and their release behavior depended on the micropores.
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