3D Biomimetic Calcified Cartilaginous Callus that Induces Type H Vessels Formation and Osteoclastogenesis (Adv. Sci. 16/2023)

Abstract

3D Biomimetic Calcified Cartilaginous Callus Based on the natural bone repair process, a 3D biomimetic calcified cartilaginous callus (PHS) is prepared using calcium ion chelation and 3D printing technology to promote the regeneration of large-segment bone defects. PHS can promote both type H vessels formation and osteoclast formation and promote bone regeneration by facilitating the expression of osteogenesis-promoting coupling factors. More details can be found in article number 2207089 by Jin Qi, Wenguo Cui, Lianfu Deng, and co-workers.