Abstract
Chronic plaque-type psoriasis is an inflammatory skin disease, where alterations can be found at the dermal-epidermal junction (DEJ) of the non-lesional (NL) skin and signs of systemic inflammation can also be detected. Periostin is also located at the DEJ, besides periostin is known to play a role in inflammatory and wound healing processes. Thus, we aimed to investigate the potential role of periostin in the pathogenesis of psoriasis. Serum and skin samples were collected from untreated and systemically treated (ST) psoriatic patients (PS) and from healthy (H) volunteers.
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