Abstract

The list of therapeutically relevant biomarkers in NSCLC is continually expanding and hence molecular profiling is of paramount importance. Tissue availability and chance of rebiopsy is a major limitation in lung cancer and sequential single gene assays lead to tissue exhaustion and inadvertent delays in institution of therapy. We sought to compare the performance of targeted next-generation sequencing (NGS) panels with traditional assays and correlate the mutational landscape in an Indian NSCLC cohort.

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