Abstract
Data suggest that in psoriasis the entire epidermis of the individuals has inherited capacity to form lesions. The uninvolved (UN) skin potentially provides a tissue environment in which lesions can develop. Since cytokines, chemokines, proteases, and their inhibitors play important roles in regulating tissue-organization, we aimed to compare these proteins between healthy (H) and uninvolved (UN) skin of patients with mild (mean PASI: 9.06) and severe (mean PASI: 28.93) psoriasis using specific protein arrays.
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