Abstract
veratrol, 18 reviews and 75 animal studies were identified. These included studies showing that resveratrol exerts neuroprotective effects (i.e., rescue of hippocampal primary neurons from oxidative damage and reduction of beta-amyloid secretion), possibly through the activation of resveratrol binding sites on neuronal membranes. The clinical and experimental studies have shown the effectiveness of resveratrol both in preventing memory deficits in animal models and modulating the pathological mechanisms of human dementia. In conclusion, the bulk of published data clearly indicates that these polyphenols have neuroprotective effects. The literature results could pave the way for improved treatment of neurodegenerative diseases of senior pets, i.e., CDS (Cognitive Dysfunction Syndrome).
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