Abstract

The LITE study (NCT03726489) is the largest US-based academic pragmatic trial in dermatology to date. It compares home v office phototherapy for psoriasis at 38 sites with goals of 1050 enrolled and equal skin type representation embedded in routine clinical care. The COVID19 pandemic resulted in profound impacts to routine dermatological care and execution of clinical research. To determine the impact of the pandemic on enrollment, we defined time periods as pre-pandemic (March 2019-March 2020) and post-pandemic (April 2020-January 1, 2022).

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