386 Efficient ex-vivo expansion of adaptive NKG2C+/CD57+ NK cells from CMV-positive donors using dendritic cells derived from the acute myeloid cell line DCOne

Abstract

BackgroundHuman cytomegalovirus (CMV) infection profoundly affects NK cell compartment, as documented by the presence of a long-lived adaptive NK cell subset co-expressing NKG2C and CD57. Several features render adaptive NK...