(385) The Evaluation of Blended Codeine Phosphate with Hydroxyzine Pamoate, Gabapentin, Ondansetron, and Docusate for the Treatment of Chronic Pain: A Patient-Centered Approach to the Pain Management “State of Emergency”

Abstract

The United States is suffering from a so-called opioid epidemic. It has been proposed that the onset of this epidemic occurs in physician offices. In November 2016, the Centers for Disease Control published guidelines for the treatment of non-cancer related pain. In this guideline, they suggested limitations as to the amount of morphine milligram equivalencies that are allowed for adequate pain relief, while limiting the complication rate. In this study, we evaluate the effectiveness of a Codeine preparation for the treatment of moderate to severe pain. The study evaluates the effectiveness of reducing MME through substituting medication with a low MME rather than weaning the patient. A trial of 20 patients was carried out. The patients were required to score their pain while on their previous medications. The score was the standardized one -10/10 methodology. The patients were then switched to a Codeine blended therapy and were asked to report on their pain, using the same methodology. The effectiveness of this treatment program is presented. P values are calculated. Of the 20 patients, 19 had excellent results with equal pain relief and no significant adverse reactions. The use of a blended codeine therapy can lower the MME without change in pain or withdrawal.