#383 : The Correlation Between Serum Estradiol, Luteinizing Hormone (LH), and Progesterone on Day Human Chronic Gonadotropin (hCG) with In Vitro Fertilisation (IVF) Outcome

Abstract

Background and Aims: Serum estradiol, LH, and progesterone have been studied for many years as they were considered to have relation with the pregnancy outcome in IVF procedure. The aim of this study is to determine the serum estradiol, LH, progesterone, biochemical pregnancy, clinical pregnancy, and ongoing pregnancy distribution of IVF patients; and to determine the correlation between serum estradiol, LH, and progesterone on day hCG with IVF outcome. Method: This is an observational study that was conducted in Yasmin IVF Clinic from 2013 until 2021. There were 416 samples. The serum estradiol, LH, and progesterone were collected from the IVF patient on day hCG. The IVF outcomes were collected by hCG blood test (biochemical pregnancy), USG (clinical pregnancy), and being checked after several months (ongoing pregnancy). The statistical analysis used IBM SPSS Statistics 26. Results: The serum estradiol, LH, progesterone, biochemical pregnancy, clinical pregnancy, and ongoing pregnancy were distributed abnormally. There is no significant difference between serum estradiol on hCG day with biochemical pregnancy (p=0.81), clinical pregnancy (p=0.205), and ongoing pregnancy (p=0.117). There is no significant difference between serum LH on hCG day with biochemical pregnancy (p=0.606), clinical pregnancy (p=0.45), and ongoing pregnancy (p=0.396). There is no significant difference between serum progesterone on hCG day with biochemical pregnancy (p=0.363), clinical pregnancy (p=0.942), and ongoing pregnancy (p=0.352). Conclusion: There is no significant difference between serum estradiol, LH, and progesterone on day hCG with IVF outcome.