38 THE ROLE OF PEAK ATRIAL LONGITUDINAL STRAIN IN HYPERTENSION HEART DISEASE AS AN INDICATOR FOR EARLY DIASTOLIC LEFT VENTRICLE IMPAIRMENT

Abstract

Background: Patient with Hypertension Heart Disease (HHD) increase LV feeling pressure and cause remodelling of LV and LA structure. That mechanism leads high pressure in LA. LA strain can be used to gain insight into LA reservoir, conduit, and pump functions. PALS is reflection of LA reservoir function. Often reduced in patient with increased LV filling pressure. LA systolic strain is very accurate marker for estimating raised pulmonary capillary wedge pressure (PCWP). PCWP (E/e') is one of the indicator for diastolic LV disfunction. Objective: Comparison PALS in patient with controlled HHD and Non-HHD as an indicator for early diastolic LV Impairment. Methods: 60 patients with normal EF (50% controlled HHD and 50% Non-HHD) were measured PALS used speckle tracking 2D echocardiography. Data were collected from mean of peak LA Strain. Distribution data of PALS was examined with Shapiro-wilk test. Mean PALS between patient with Controlled HHD and Non-HHD were compared, examined used t-pair test. Result: Total sample 56,7% male and 43,3% female. Mean of hypertension 9 years, age 58 vs 54 (HHD vs Non-HHD), E/e' 8,34 vs 6,06 (HHD vs Non-HHD), LAVI 24,04 vs 18,03 (HHD vs NonHHD). Comparison between PALS in HHD and Non-HHD have significant result (25,05% vs 46,36%, p=0,001). Conclusion: Patient with HHD decrease mean of PALS. Decrease of PALS is indicated with increased of LV filling pressure. Patient with low PALS can be an indicator for early diastolic LV impairment leading to HFpEF.