Abstract
Testosterone Deficiency was added to the 2018 AUA Guidelines with 31 Statements, with a moderate recommendation in informing patients about improvement of erectile function (EF) under treatment. In an ongoing registry study in a single urology practice, we monitored EF for up to 12 years. We report data from 823 men with symptomatic hypogonadism participating in a registry study started in 2004. 428 men received testosterone undecanoate (TU) injections 1000 mg/12 weeks following an initial 6-week interval (T-group), 395 opted against TTh and served as controls (CTRL). Changes over time between groups were compared by a mixed effects model for repeated measures with a random effect for intercept and fixed effects for time, group and their interaction and adjusted for age, weight, waist circumference, blood pressure, fasting glucose, lipids and quality of life to account for baseline differences between groups. Mean (median) follow-up: T-group 8±3 (9), CTRL 9±2 (10) years. Total observation time: T-group 3594, CTRL 3522 years. Baseline age: 58±7 in T-group, 64±5 years in CTRL.
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