Abstract

Neutrophils are critical to the inflammatory process and tissue homeostasis. The lobulated neutrophil nucleus has a unique membrane composition, yielding a deformable structure that is highly responsive to the environment and allows for efficient migration to the site of inflammation. Furthermore, neutrophils possess an arsenal of antimicrobial defense mechanisms, including the expulsion of neutrophil extracellular traps (NETs), composed of nuclear DNA studded with cellular and antimicrobial proteins.

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