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Abstract
Chronic musculoskeletal pain (CMP) conditions have a strong central component to their pain, and are associated with significant pain and disability that is difficult to treat. The current study tested the effects of SCS in an animal model of chronic muscle pain that mimics the symptoms of CMP. Ten days after an epidural SCS lead was implanted into the spinal cord (L3-L4) of Sprague-Dawley rats, chronic muscle pain was induced by two injections of pH 4 saline into one gastrocnemius muscle, 5 days apart.
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