Abstract
Sensory innervation is a combination of endings associated with corpuscular structures located in dermis and free nerve endings innervating dermis and epidermis, reaching the uppermost viable layer of skin. Cutaneous innervation is closely associated with major skin functions. For example, skin chronological aging and photoaging are associated with changes in innervation such as the decrease of intra-epidermal nerve fibre density on face. For centuries, bee products and specifically honey have been utilized for wound healing.
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