Abstract
Introduction/Aims: ErbB receptors are trans-membrane glycoproteins with tyrosine kinase activity. Especially in cancer, they are implicated in cell proliferation, transformation, angiogenesis, migration and invasion. The expression of ErbB receptors, has not been studied well in patients with CIN 3 and cervical cancer. The main aim of our study was to access EGF system receptors status among young patients with CIN 3 and cervical cancer. Method: We evaluated retrospectively tissue specimens from 75 patients with CIN 3 and cervical cancer, that have been treated in Gynaecological Oncology Unit of the University of Patras.
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