Abstract

Patients with unilateral varicocele, grade 3, (n=11), were analyzed to study if there are morphological or fuctional alterations in the testes. They were classified according to genital stage given GnRH (100 mcg) and hCG (50 U/kg/dose. 5 days) and underwent bilateral testicular biopsy. Testicular volume (TV) was measured and differences > 2 cm3 were considered significant Basal testoterone (T) and peak LH, FSH and T were similar to the control group. There was no difference in basal LH and FSH between groups G1, G2, G3+4. Tubular diameter (TD) and area (TA) are showed in the table. In the five cases with decreased testicular volume, there was a higher TD on the Va side. Six patients didn't have a reduction in testicular volume and only two had a difference in TD between both sides. There was a tendency for a decrease in testicular volume and an increase in TD advancing pubertal development.

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