359 “Pop” the Pylorus! Per Oral Pyloro-Myotomy- a Novel Submucosal Endoscopy Technique

Abstract

Endoscopic submucosal dissection (ESD) and Per Oral Endoscopic Myotomy (POEM) procedures are elegant endoscopic techniques to explore the submucosal space and to offer minimally invasive approach to treat diseases that otherwise require invasive surgery. We envisioned using the submucosal space to access pylorus and to perform pyloro-myotomy. To our knowledge this has not been reported before. Potential applications of this technique could be in the endoscopic treatment of gastroparesis, pylorospasm, direct visualization injections to pylorus and other GI muscles and even in full thickness resection of gastric sub-epithelial neoplasms.