Abstract
Diethyl 2-alkyl-2-(benzyloxycarbonylamino)malonates were saponified, activated with oxalyl chloride, and treated with primary aromatic amines. This gave 3,5-disubstituted hydantoin-5-carboxamides. As second products, 2-alkyl-2-formamido-<i>N</i> <sup>1</sup>,<i>N</i> <sup>3</sup>-bis(aryl)malonamides were isolated. The formation of both types of products is expected to include a cyclization to 2-alkoxyoxazol-5(4<i>H</i>)-ones, acting as precursor for the hydantoins, or a further transformation to <i>N</i>-carboxy anhydrides, their chloride-promoted ring opening, and subsequent conversion to give the bis(aryl)malonamides.
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