Abstract
Previous cross-sectional studies have shown that skin microbiomes of adults and older children are distinct from those of younger children. However, the influence of sexual maturation on the human skin microbiome in individuals followed over time has not been studied as extensively. We performed a prospective, longitudinal study to investigate puberty-dependent shifts in skin microbiota. Twelve healthy children (4 girls and 8 boys) were evaluated every 6-18 months for up to 6 years at the outpatient dermatology clinic in the National Institute of Health Clinical Center.
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