350Exposure Investigation and Infection Prevention Measures for a Patient with Confirmed NDM-1 Producing Klebsiella pneumoniae

Abstract

Wound Cultures Obtained: 9 Number of Wound Cultures Growing CRE: 1 Number of Wound Cultures Growing NDM-1 CRE: 0 Carbapenem-resistant Enterobacteriaceae (CRE) are a class of bacteria with several resistance mechanisms, including the production of carbapenemase, an enzyme that breaks down carbapenem antibiotics. The New Delhi metallo-beta-lactamase-1 (NDM-1) enzyme was first discovered in India. It has become endemic in India and Pakistan, especially in healthcare settings. It was first seen in the United States in 2010 and has been 16 states so far (CDC, 2014). The first case of NDM-1 CRE at The Johns Hopkins Hospital (JHH) was identified in February 2014. The patient, whom had traveled to India but was never hospitalized there., was admitted to JHH in late January 2014. He was admitted on two surgical intensive care units and one surgical unit prior to being isolated. Exposure Investigation and Infection Prevention Measures for a Patient with Confirmed NDM-1 Producing Klebsiella pneumoniae