35. Spontaneous bacterial peritonitis in patients with chronic liver disease

Abstract

Background and Aims: To determine the prevalence of SBP patients with chronic liver disease as well as to identify any difference in biochcmical parameters of ascitic fluid in patients with and without SBP. Methods: 105 patients with cirrhosis and ascites of the age 11 years and above reporting in department of Gastroentetology and Hepatology of MLN medical college, Allahabad were included in the study from 2016 October 2017. The diagnosis of cirrhosis was made on history, clinical examination and ultrasonographic findings. These patients were subjected to ascitic fluid paracentesis and were divided into SBP and non-SBP groups on the basis of ascitic fluid culture and routine examination. Patients in two groups were also categorised on the basis of Child Pugh criteria. Results: The study included a total of 105 cases (77 males and 28 females) having Cirrhosis and ascites. The mean age of these patients was 44.40 ± 16.32 years. On the basis of routine examination and culture of ascitic fluid from these cases, 20 (19.05%) were diagnosed to have SBP. E. coli was the most frequent cultured organism. It was isolated in 3 (15%) cases with SBP. One case (5%) of Klebsiella species was also reported. SBP was more common in CTP class C (90%) as was the observation with Sterile cirrhotic acsitis. Conclusions: This study reaffirms that SBP is a common and potentially fatal complication in cirrhotic patients with ascites. E. coli is the most frequent offending organism causing his condition. Moreover SBP is more common in patients of CTP class C. The authors have none to declare.