Abstract
•First Described: 1957 (New Zealand, Fastier).•Causes: FCV, family Caliciviridae, genus Vesivirus.•Affected Hosts: Domestic cat and many other Felidae. Similar viruses also isolated occasionally from dogs.•Geographic Distribution: Worldwide.•Primary Mode of Transmission: Oronasal, fomite spread.•Major Clinical Signs: Oral ulceration, oculonasal discharges, lethargy. Less commonly lameness, lower respiratory tract infection, and signs of enteritis. Rare virulent forms may also cause edema, icterus, skin necrosis, and death.•Differential Diagnosis: Differential diagnoses for FCV infection are other respiratory viral infections (FCV, influenza viruses), infections with bacteria such as Bordetella bronchiseptica, Mycoplasma spp., Streptococcus spp., or Chlamydia felis; other causes of rhinitis such as cryptococcosis, aspergillosis, neoplasia, foreign bodies, chronic idiopathic feline rhinosinusitis, nasopharyngeal stenosis, or nasopharyngeal polyps; feline chronic airway disease. For cats with oral ulcerations, exposure to caustic substances may be suspected.•Human Health Significance: None known.
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