34993 Aggressive squamous cell carcinoma in setting of Huriez syndrome

Abstract

A 63-year-old man presented for a painful mass on his right thumbnail that had been present for several months. On examination, he had nail dystrophy and several ventral pterygia. Most interestingly, scleroatrophy of the distal upper extremities were noted on all 10 digits and the palms had marked keratoderma. Further history revealed that he had had keratoderma since childhood. History also noted conical dentition that led to dentures at the age of 17, and nail abnormalities. His condition went undiagnosed in childhood, and he did not follow up with a dermatologist.