347 — Development of an electrochemical catalyst-binder electrode for glucose measurement

Abstract

First results about glucose measurement with a catalyst-binder electrode in phosphate buffer solution at 37°C are shown. A new type of compact, electrochemical, glucose sensor was developed, which consists of three electrodes: the working electrode, a 0.5 mm diameter glass-sheathed platinum wire, was covered with a mixture of catalyst and binder, and two Ag⋎AgCl electrodes are used as the reference and the rejuvenating electrode respectively. Mixtures of the catalyst platinum black, palladium black and platinum black adsorbed at charcoal with the binders PMMA and PVA were investigated for various mixing proportions. The glucose concentration dependence of the sensor behaviour was studied by means of cyclic voltammetry, potentiostatic measurements of currents—time curves and non-equilibrium measurements with a periodic alternation of rejuvenation and measurement. For the last-mentioned measuring method a special programmable control unit was designed. The calibration curves for the determination of glucose measured by using the control unit exhibit a nearly linear dependence up to a concentration of 44.4 m M.