346 The Association Between Toxic Life Stress and Semen Quality

Abstract

About 15% of couples who are of childbearing age cannot achieve a wanted pregnancy and about 50% of infertility is related to male factor. Stress is one of the determinants of infertility, which leads to disruption of spermatogenesis. We undertook a retrospective study of men to elucidate whether early life stress might be a contributing factor that negatively affects semen quality in who are infertile. In this retrospective study we examine 468 idiopathic infertile men between the ages of 18 to 56 years to elucidate whether early life stress might be a contributing factor that negatively affects semen quality of them. A physical examination was performed by a physician-urologist for all eligible participants to insure they have no problems in their genitals system, followed by participants completed early life stress questionnaire and finally their semen were collected by masturbation. The results showed that the median of sperm counts and progressive motility in the participants who their parents were divorced in their childhood, were significantly lower than others. In the infertile male who one of their parents died in their childhood, the median of immotile sperm was significantly higher also people who had experienced physical and sexual abuse or physical and emotional neglect in their childhood or adolescence, had significantly lower sperm counts also lower normal morphology than others. Furthermore, participants who work in their childhood to help financial of their families had lower progressive motility of sperm.