Abstract

Erenumab is a calcitonin gene-related peptide receptor antagonist monoclonal antibody indicated for migraine prophylaxis in treatment resistant patients first approved in 2018. In the pivotal trials, the only reported cutaneous adverse effect was injection site pain. Here, we report a 40-year-old Caucasian woman who presented with a polymorphic eruption of the extremities and trunk that initially presented in the days following her first injection of erenumab. The eruption was urticarial on the trunk and papulosquamous on the extremities.

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