Abstract
Verrucous venous malformations (VVMs) are rare congenital vascular malformations that present at birth or in adulthood as a linear vascular plaque typically unilateral on the lower extremity with reactive skin changes. VVMs are frequently misdiagnosed due to their clinical resemblance to other vascular malformations. Gold standard for diagnosis is histopathologic evaluation of a deep tissue section. Recently, a missense mutation MAP3K3 has been linked to VVM. Large vascular malformations are associated with local intravascular coagulopathy (LIC) that carry an increased thromboembolic risk, especially within low-flow venous malformations.
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