Abstract
Purpose: The placenta-derived mesenchymal stem cells have great interest as a promising cell source for regenerative medicine due to non-invasive collection, readily availability, high expansion capacity, and low immunogenicity. We investigated the feasibility of transplanting placenta-derived MSCs and a hyaluronic acid (HA) hydrogel composite to repair full-thickness articular cartilage defects and determine whether the transplantation of various concentrations of placenta-derived MSCs with 4% hyaluronic acid (HA) hydrogel promoted articular cartilage repair in a rabbit model.
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