Abstract
Psoriasis is a chronic inflammatory skin disease caused by an IL-23- and IL-17 driven immune response. Monocytes are regarded as key immune regulatory cells, which can be divided into three well-defined subsets: classical monocytes, intermediate monocytes, and non-classical monocytes (ncMo). The function of ncMo in skin inflammation remains largely unknown. Yet, our previous studies on slan+ (6-sulfo LacNAc) ncMo suggested that these cells contribute to human psoriasis skin inflammation. We here report on the role of ncMo in a model of psoriasis-like skin inflammation induced by imiquimod (IMQ).
Talk to us
Join us for a 30 min session where you can share your feedback and ask us any queries you have
Schedule a callDisclaimer: All third-party content on this website/platform is and will remain the property of their respective owners and is provided on "as is" basis without any warranties, express or implied. Use of third-party content does not indicate any affiliation, sponsorship with or endorsement by them. Any references to third-party content is to identify the corresponding services and shall be considered fair use under The CopyrightLaw.
