Abstract
Primary intracranial sarcomas comprise a rare and diverse group of tumors that frequently pose diagnostic challenges and may be mistaken for glial neoplasms. Despite tremendous efforts to refine the molecular classification of sarcomas, the genomic landscape of primary intracranial sarcomas remains poorly defined. To this end, we investigated the clinicopathologic features of unclassified primary intracranial sarcomas in 6 patients. All cases were analyzed using next-generation targeted sequencing covering exons of 447 genes and 191 introns across 60 genes.
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