Abstract
Three-dimensional (3D) cultures use the property of some cells to self-organize in generate structures that can be programmed to represent an organ or a pathology. The ductal compartment in salivary gland has been identified as the location harboring stem cells.Salivary glands has been investigated using in vivo or ex vivo rudiment culture models. The specific requirements of the niche remain unclear for many cell types, including the pro-acinar cells that give rise to secretory acinar epithelial cells that produce saliva.
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Schedule a callMore From: Annals of oncology : official journal of the European Society for Medical Oncology
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